A phylogenetically distinct Middle East respiratory syndrome coronavirus detected in a dromedary calf from a closed dairy herd in Dubai with rising seroprevalence with age
Identifieur interne : 001916 ( Main/Exploration ); précédent : 001915; suivant : 001917A phylogenetically distinct Middle East respiratory syndrome coronavirus detected in a dromedary calf from a closed dairy herd in Dubai with rising seroprevalence with age
Auteurs : Ulrich Wernery [Émirats arabes unis] ; Ihassab El Rasoul [Émirats arabes unis] ; Emily Ym Wong [République populaire de Chine] ; Marina Joseph [Émirats arabes unis] ; Yixin Chen [République populaire de Chine] ; Shanty Jose [Émirats arabes unis] ; Alan Kl Tsang [République populaire de Chine] ; Nissy Annie Georgy Patteril [Émirats arabes unis] ; Honglin Chen [République populaire de Chine] ; Shyna K. Elizabeth [Émirats arabes unis] ; Kwok-Yung Yuen [République populaire de Chine] ; Sunitha Joseph [Émirats arabes unis] ; Ningshao Xia [République populaire de Chine] ; Renate Wernery [Émirats arabes unis] ; Susanna Kp Lau [République populaire de Chine] ; Patrick Cy Woo [République populaire de Chine]Source :
- Emerging Microbes & Infections [ 2222-1751 ] ; 2015.
Descripteurs français
- KwdFr :
- Animaux, Appareil respiratoire (virologie), Arabie saoudite (épidémiologie), Chameaux, Coronavirus du syndrome respiratoire du Moyen-Orient (génétique), Coronavirus du syndrome respiratoire du Moyen-Orient (physiologie), Flambées de maladies (), Flambées de maladies (médecine vétérinaire), Industrie laitière, Infections à coronavirus (génétique), Infections à coronavirus (médecine vétérinaire), Infections à coronavirus (épidémiologie), Phylogénie, Tropisme viral, Études séroépidémiologiques.
- MESH :
- génétique : Coronavirus du syndrome respiratoire du Moyen-Orient, Infections à coronavirus.
- médecine vétérinaire : Flambées de maladies, Infections à coronavirus.
- physiologie : Coronavirus du syndrome respiratoire du Moyen-Orient.
- virologie : Appareil respiratoire.
- épidémiologie : Arabie saoudite, Infections à coronavirus.
- Animaux, Chameaux, Flambées de maladies, Industrie laitière, Phylogénie, Tropisme viral, Études séroépidémiologiques.
English descriptors
- KwdEn :
- Animals, Camelus, Coronavirus Infections (epidemiology), Coronavirus Infections (genetics), Coronavirus Infections (veterinary), Dairying, Disease Outbreaks (statistics & numerical data), Disease Outbreaks (veterinary), Middle East Respiratory Syndrome Coronavirus (genetics), Middle East Respiratory Syndrome Coronavirus (physiology), Phylogeny, Respiratory System (virology), Saudi Arabia (epidemiology), Seroepidemiologic Studies, Viral Tropism.
- MESH :
- epidemiology : Coronavirus Infections, Saudi Arabia.
- genetics : Coronavirus Infections, Middle East Respiratory Syndrome Coronavirus.
- physiology : Middle East Respiratory Syndrome Coronavirus.
- statistics & numerical data : Disease Outbreaks.
- veterinary : Coronavirus Infections, Disease Outbreaks.
- virology : Respiratory System.
- Animals, Camelus, Dairying, Phylogeny, Seroepidemiologic Studies, Viral Tropism.
Abstract
Middle East respiratory syndrome coronavirus (MERS-CoV) was detected by monoclonal antibody-based nucleocapsid protein-capture enzyme-linked immunosorbent assay (ELISA), RNA detection, and viral culture from the nasal sample of a 1-month-old dromedary calf in Dubai with sudden death. Whole genome phylogeny showed that this MERS-CoV strain did not cluster with the other MERS-CoV strains from Dubai that we reported recently. Instead, it formed a unique branch more closely related to other MERS-CoV strains from patients in Qatar and Hafr-Al-Batin in Saudi Arabia, as well as the MERS-CoV strains from patients in the recent Korean outbreak, in which the index patient acquired the infection during travel in the eastern part of the Arabian Peninsula. Non-synonymous mutations, resulting in 11 unique amino acid differences, were observed between the MERS-CoV genome from the present study and all the other available MERS-CoV genomes. Among these 11 unique amino acid differences, four were found in ORF1ab, three were found in the S1 domain of the spike protein, and one each was found in the proteins encoded by ORF4b, ORF5, envelope gene, and ORF8. MERS-CoV detection for all other 254 dromedaries in this closed dairy herd was negative by nucleocapsid protein-capture ELISA and RNA detection. MERS-CoV IgG sero-positivity gradually increased in dromedary calves with increasing age, with positivity rates of 75% at zero to three months, 79% at four months, 89% at five to six months, and 90% at seven to twelve months. The development of a rapid antigen detection kit for instantaneous diagnosis is warranted.
Url:
DOI: 10.1038/emi.2015.74
PubMed: 26632876
PubMed Central: 4715164
Affiliations:
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Le document en format XML
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Rasoul</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Nad Al Sheba Camel Dairy Farm</institution>, Dubai,<country>United Arab Emirates</country></nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Wong, Emily Ym" sort="Wong, Emily Ym" uniqKey="Wong E" first="Emily Ym" last="Wong">Emily Ym Wong</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Department of Microbiology, The University of Hong Kong</institution>, Hong Kong,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Joseph, Marina" sort="Joseph, Marina" uniqKey="Joseph M" first="Marina" last="Joseph">Marina Joseph</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Central Veterinary Research Laboratory</institution>, Dubai,<country>United Arab Emirates</country></nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Chen, Yixin" sort="Chen, Yixin" uniqKey="Chen Y" first="Yixin" last="Chen">Yixin Chen</name><affiliation wicri:level="1"><nlm:aff id="aff4"><institution>State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, Xiamen University</institution>, Xiamen 361102, Fujian Province,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff5"><institution>National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, Xiamen University</institution>, Xiamen 361102, Fujian Province,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Jose, Shanty" sort="Jose, Shanty" uniqKey="Jose S" first="Shanty" last="Jose">Shanty Jose</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Central Veterinary Research Laboratory</institution>, Dubai,<country>United Arab Emirates</country></nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Tsang, Alan Kl" sort="Tsang, Alan Kl" uniqKey="Tsang A" first="Alan Kl" last="Tsang">Alan Kl Tsang</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Department of Microbiology, The University of Hong Kong</institution>, Hong Kong,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Patteril, Nissy Annie Georgy" sort="Patteril, Nissy Annie Georgy" uniqKey="Patteril N" first="Nissy Annie Georgy" last="Patteril">Nissy Annie Georgy Patteril</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Central Veterinary Research Laboratory</institution>, Dubai,<country>United Arab Emirates</country></nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Chen, Honglin" sort="Chen, Honglin" uniqKey="Chen H" first="Honglin" last="Chen">Honglin Chen</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Department of Microbiology, The University of Hong Kong</institution>, Hong Kong,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff6"><institution>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong</institution>, Hong Kong,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Research Centre of Infection and Immunology, The University of Hong Kong</institution>, Hong Kong,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff8"><institution>Carol Yu Centre for Infection, The University of Hong Kong</institution>, Hong Kong,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Elizabeth, Shyna K" sort="Elizabeth, Shyna K" uniqKey="Elizabeth S" first="Shyna K" last="Elizabeth">Shyna K. Elizabeth</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Central Veterinary Research Laboratory</institution>, Dubai,<country>United Arab Emirates</country></nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Yuen, Kwok Yung" sort="Yuen, Kwok Yung" uniqKey="Yuen K" first="Kwok-Yung" last="Yuen">Kwok-Yung Yuen</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Department of Microbiology, The University of Hong Kong</institution>, Hong Kong,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff6"><institution>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong</institution>, Hong Kong,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Research Centre of Infection and Immunology, The University of Hong Kong</institution>, Hong Kong,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff8"><institution>Carol Yu Centre for Infection, The University of Hong Kong</institution>, Hong Kong,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Joseph, Sunitha" sort="Joseph, Sunitha" uniqKey="Joseph S" first="Sunitha" last="Joseph">Sunitha Joseph</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Central Veterinary Research Laboratory</institution>, Dubai,<country>United Arab Emirates</country></nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Xia, Ningshao" sort="Xia, Ningshao" uniqKey="Xia N" first="Ningshao" last="Xia">Ningshao Xia</name><affiliation wicri:level="1"><nlm:aff id="aff4"><institution>State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, Xiamen University</institution>, Xiamen 361102, Fujian Province,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff5"><institution>National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, Xiamen University</institution>, Xiamen 361102, Fujian Province,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Wernery, Renate" sort="Wernery, Renate" uniqKey="Wernery R" first="Renate" last="Wernery">Renate Wernery</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Central Veterinary Research Laboratory</institution>, Dubai,<country>United Arab Emirates</country></nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lau, Susanna Kp" sort="Lau, Susanna Kp" uniqKey="Lau S" first="Susanna Kp" last="Lau">Susanna Kp Lau</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Department of Microbiology, The University of Hong Kong</institution>, Hong Kong,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff6"><institution>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong</institution>, Hong Kong,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Research Centre of Infection and Immunology, The University of Hong Kong</institution>, Hong Kong,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff8"><institution>Carol Yu Centre for Infection, The University of Hong Kong</institution>, Hong Kong,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Woo, Patrick Cy" sort="Woo, Patrick Cy" uniqKey="Woo P" first="Patrick Cy" last="Woo">Patrick Cy Woo</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Department of Microbiology, The University of Hong Kong</institution>, Hong Kong,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff6"><institution>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong</institution>, Hong Kong,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Research Centre of Infection and Immunology, The University of Hong Kong</institution>, Hong Kong,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff8"><institution>Carol Yu Centre for Infection, The University of Hong Kong</institution>, Hong Kong,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Emerging Microbes & Infections</title><idno type="eISSN">2222-1751</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Camelus</term><term>Coronavirus Infections (epidemiology)</term><term>Coronavirus Infections (genetics)</term><term>Coronavirus Infections (veterinary)</term><term>Dairying</term><term>Disease Outbreaks (statistics & numerical data)</term><term>Disease Outbreaks (veterinary)</term><term>Middle East Respiratory Syndrome Coronavirus (genetics)</term><term>Middle East Respiratory Syndrome Coronavirus (physiology)</term><term>Phylogeny</term><term>Respiratory System (virology)</term><term>Saudi Arabia (epidemiology)</term><term>Seroepidemiologic Studies</term><term>Viral Tropism</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Appareil respiratoire (virologie)</term><term>Arabie saoudite (épidémiologie)</term><term>Chameaux</term><term>Coronavirus du syndrome respiratoire du Moyen-Orient (génétique)</term><term>Coronavirus du syndrome respiratoire du Moyen-Orient (physiologie)</term><term>Flambées de maladies ()</term><term>Flambées de maladies (médecine vétérinaire)</term><term>Industrie laitière</term><term>Infections à coronavirus (génétique)</term><term>Infections à coronavirus (médecine vétérinaire)</term><term>Infections à coronavirus (épidémiologie)</term><term>Phylogénie</term><term>Tropisme viral</term><term>Études séroépidémiologiques</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Saudi Arabia</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Coronavirus Infections</term><term>Middle East Respiratory Syndrome Coronavirus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="médecine vétérinaire" xml:lang="fr"><term>Flambées de maladies</term><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Disease Outbreaks</term></keywords><keywords scheme="MESH" qualifier="veterinary" xml:lang="en"><term>Coronavirus Infections</term><term>Disease Outbreaks</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Appareil respiratoire</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Respiratory System</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Arabie saoudite</term><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Camelus</term><term>Dairying</term><term>Phylogeny</term><term>Seroepidemiologic Studies</term><term>Viral Tropism</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Chameaux</term><term>Flambées de maladies</term><term>Industrie laitière</term><term>Phylogénie</term><term>Tropisme viral</term><term>Études séroépidémiologiques</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Middle East respiratory syndrome coronavirus (MERS-CoV) was detected by monoclonal antibody-based nucleocapsid protein-capture enzyme-linked immunosorbent assay (ELISA), RNA detection, and viral culture from the nasal sample of a 1-month-old dromedary calf in Dubai with sudden death. Whole genome phylogeny showed that this MERS-CoV strain did not cluster with the other MERS-CoV strains from Dubai that we reported recently. Instead, it formed a unique branch more closely related to other MERS-CoV strains from patients in Qatar and Hafr-Al-Batin in Saudi Arabia, as well as the MERS-CoV strains from patients in the recent Korean outbreak, in which the index patient acquired the infection during travel in the eastern part of the Arabian Peninsula. Non-synonymous mutations, resulting in 11 unique amino acid differences, were observed between the MERS-CoV genome from the present study and all the other available MERS-CoV genomes. Among these 11 unique amino acid differences, four were found in ORF1ab, three were found in the S1 domain of the spike protein, and one each was found in the proteins encoded by ORF4b, ORF5, envelope gene, and ORF8. MERS-CoV detection for all other 254 dromedaries in this closed dairy herd was negative by nucleocapsid protein-capture ELISA and RNA detection. MERS-CoV IgG sero-positivity gradually increased in dromedary calves with increasing age, with positivity rates of 75% at zero to three months, 79% at four months, 89% at five to six months, and 90% at seven to twelve months. The development of a rapid antigen detection kit for instantaneous diagnosis is warranted.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République populaire de Chine</li><li>Émirats arabes unis</li></country></list><tree><country name="Émirats arabes unis"><noRegion><name sortKey="Wernery, Ulrich" sort="Wernery, Ulrich" uniqKey="Wernery U" first="Ulrich" last="Wernery">Ulrich Wernery</name></noRegion><name sortKey="Elizabeth, Shyna K" sort="Elizabeth, Shyna K" uniqKey="Elizabeth S" first="Shyna K" last="Elizabeth">Shyna K. Elizabeth</name><name sortKey="Jose, Shanty" sort="Jose, Shanty" uniqKey="Jose S" first="Shanty" last="Jose">Shanty Jose</name><name sortKey="Joseph, Marina" sort="Joseph, Marina" uniqKey="Joseph M" first="Marina" last="Joseph">Marina Joseph</name><name sortKey="Joseph, Sunitha" sort="Joseph, Sunitha" uniqKey="Joseph S" first="Sunitha" last="Joseph">Sunitha Joseph</name><name sortKey="Patteril, Nissy Annie Georgy" sort="Patteril, Nissy Annie Georgy" uniqKey="Patteril N" first="Nissy Annie Georgy" last="Patteril">Nissy Annie Georgy Patteril</name><name sortKey="Rasoul, Ihassab El" sort="Rasoul, Ihassab El" uniqKey="Rasoul I" first="Ihassab El" last="Rasoul">Ihassab El Rasoul</name><name sortKey="Wernery, Renate" sort="Wernery, Renate" uniqKey="Wernery R" first="Renate" last="Wernery">Renate Wernery</name></country><country name="République populaire de Chine"><noRegion><name sortKey="Wong, Emily Ym" sort="Wong, Emily Ym" uniqKey="Wong E" first="Emily Ym" last="Wong">Emily Ym Wong</name></noRegion><name sortKey="Chen, Honglin" sort="Chen, Honglin" uniqKey="Chen H" first="Honglin" last="Chen">Honglin Chen</name><name sortKey="Chen, Honglin" sort="Chen, Honglin" uniqKey="Chen H" first="Honglin" last="Chen">Honglin Chen</name><name sortKey="Chen, Honglin" sort="Chen, Honglin" uniqKey="Chen H" first="Honglin" last="Chen">Honglin Chen</name><name sortKey="Chen, Honglin" sort="Chen, Honglin" uniqKey="Chen H" first="Honglin" last="Chen">Honglin Chen</name><name sortKey="Chen, Yixin" sort="Chen, Yixin" uniqKey="Chen Y" first="Yixin" last="Chen">Yixin Chen</name><name sortKey="Chen, Yixin" sort="Chen, Yixin" uniqKey="Chen Y" first="Yixin" last="Chen">Yixin Chen</name><name sortKey="Lau, Susanna Kp" sort="Lau, Susanna Kp" uniqKey="Lau S" first="Susanna Kp" last="Lau">Susanna Kp Lau</name><name sortKey="Lau, Susanna Kp" sort="Lau, Susanna Kp" uniqKey="Lau S" first="Susanna Kp" last="Lau">Susanna Kp Lau</name><name sortKey="Lau, Susanna Kp" sort="Lau, Susanna Kp" uniqKey="Lau S" first="Susanna Kp" last="Lau">Susanna Kp Lau</name><name sortKey="Lau, Susanna Kp" sort="Lau, Susanna Kp" uniqKey="Lau S" first="Susanna Kp" last="Lau">Susanna Kp Lau</name><name sortKey="Tsang, Alan Kl" sort="Tsang, Alan Kl" uniqKey="Tsang A" first="Alan Kl" last="Tsang">Alan Kl Tsang</name><name sortKey="Woo, Patrick Cy" sort="Woo, Patrick Cy" uniqKey="Woo P" first="Patrick Cy" last="Woo">Patrick Cy Woo</name><name sortKey="Woo, Patrick Cy" sort="Woo, Patrick Cy" uniqKey="Woo P" first="Patrick Cy" last="Woo">Patrick Cy Woo</name><name sortKey="Woo, Patrick Cy" sort="Woo, Patrick Cy" uniqKey="Woo P" first="Patrick Cy" last="Woo">Patrick Cy Woo</name><name sortKey="Woo, Patrick Cy" sort="Woo, Patrick Cy" uniqKey="Woo P" first="Patrick Cy" last="Woo">Patrick Cy Woo</name><name sortKey="Xia, Ningshao" sort="Xia, Ningshao" uniqKey="Xia N" first="Ningshao" last="Xia">Ningshao Xia</name><name sortKey="Xia, Ningshao" sort="Xia, Ningshao" uniqKey="Xia N" first="Ningshao" last="Xia">Ningshao Xia</name><name sortKey="Yuen, Kwok Yung" sort="Yuen, Kwok Yung" uniqKey="Yuen K" first="Kwok-Yung" last="Yuen">Kwok-Yung Yuen</name><name sortKey="Yuen, Kwok Yung" sort="Yuen, Kwok Yung" uniqKey="Yuen K" first="Kwok-Yung" last="Yuen">Kwok-Yung Yuen</name><name sortKey="Yuen, Kwok Yung" sort="Yuen, Kwok Yung" uniqKey="Yuen K" first="Kwok-Yung" last="Yuen">Kwok-Yung Yuen</name><name sortKey="Yuen, Kwok Yung" sort="Yuen, Kwok Yung" uniqKey="Yuen K" first="Kwok-Yung" last="Yuen">Kwok-Yung Yuen</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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